What Are GLP-1 Medications?
GLP-1 receptor agonists are a class of FDA-approved medications that have transformed the landscape of medical weight management. Originally developed for type 2 diabetes, these medications have shown remarkable efficacy for weight loss, leading to their approval specifically for chronic weight management.
GLP-1 stands for glucagon-like peptide-1, a hormone naturally produced in your gut after eating. These medications mimic this hormone, activating the same receptors to produce powerful effects on appetite, digestion, and metabolism.
How Do They Work?
GLP-1 medications work through several mechanisms. First, they slow gastric emptying, meaning food stays in your stomach longer, helping you feel full after smaller meals. Second, they act on appetite centers in the brain to reduce hunger and cravings. Third, they help regulate blood sugar levels, preventing the spikes and crashes that can trigger overeating.
Semaglutide vs. Tirzepatide
At Harbor, we offer two GLP-1 options. Harbor Steady uses semaglutide, a well-established GLP-1 receptor agonist with extensive clinical data supporting its safety and efficacy. Harbor Accelerate uses tirzepatide, a newer dual-action medication that activates both GLP-1 and GIP receptors, which clinical trials suggest may produce greater average weight loss.
What to Expect
Most patients begin to notice reduced appetite within the first week or two. Clinically meaningful weight loss typically becomes apparent within the first month, with results continuing to improve over 3 to 6 months. Your Harbor clinician will start you at a lower dose and gradually increase it to help minimize side effects and optimize results.
Is It Right for You?
GLP-1 medications are most appropriate for adults with a BMI of 27 or higher who want physician-guided support for their weight loss journey. Our quick online assessment helps determine if you are a good candidate. A licensed clinician reviews every case to ensure the treatment is safe and appropriate for your individual health profile.